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iShares Biotechnology (IBB)Overvalued or undervalued?
Look-through valuation · Theme · Expense ratio 0.45 % · ISIN US4642875565
Price history (since 2001)
Monthly close since 2001. Price shows performance, the valuation verdict is in the look-through above.
Top holdings
| Holding | Weight | vs fair value | Quality |
|---|---|---|---|
| Gilead Sciences Inc GILD | 8.1 % | +34.4 % | 81 |
| Amgen Inc AMGN | 7.7 % | +10.0 % | 63 |
| Vertex Pharmaceuticals Inc VRTX | 7.6 % | +15.6 % | 79 |
| Regeneron Pharmaceuticals Inc REGN | 5.3 % | +69.3 % | 73 |
| Moderna Inc MRNA | 5.0 % | n/a | n/a |
| Natera Inc NTRA | 3.9 % | −94.4 % | 40 |
| argenx NV ADR ARGX | 3.8 % | +13.1 % | 71 |
| Illumina Inc ILMN | 3.0 % | +9.0 % | 81 |
| Revolution Medicines Inc RVMD | 2.8 % | n/a | n/a |
| Biogen Inc BIIB | 2.4 % | +8.5 % | 61 |
| BeiGene, Ltd. ONC | 2.2 % | −19.5 % | 71 |
| Alnylam Pharmaceuticals Inc ALNY | 2.2 % | −2.7 % | 68 |
| Incyte Corporation INCY | 1.6 % | +85.4 % | 87 |
| Insmed Inc INSM | 1.6 % | n/a | n/a |
| United Therapeutics Corporation UTHR | 1.6 % | +44.9 % | 73 |
| Genmab AS GMAB | 1.5 % | n/a | n/a |
| Roivant Sciences Ltd ROIV | 1.4 % | n/a | n/a |
| Neurocrine Biosciences Inc NBIX | 1.1 % | +58.2 % | 69 |
| Charles River Laboratories CRL | 1.0 % | −59.9 % | 59 |
| Exelixis Inc EXEL | 1.0 % | +83.4 % | 94 |
| Ascendis Pharma AS ASND | 1.0 % | −84.8 % | 55 |
| Medpace Holdings Inc MEDP | 1.0 % | +10.4 % | 86 |
| Halozyme Therapeutics Inc HALO | 0.9 % | +17.0 % | 79 |
| BridgeBio Pharma Inc BBIO | 0.9 % | n/a | n/a |
| Bio-Techne Corp TECH | 0.8 % | −29.6 % | 78 |
Fair value and quality per position come from the same valuation as our stock pages. Showing the 25 largest of 235 disclosed positions. "n/a" means the position is not (yet) in our stock universe and does not enter the average.
The 10 most cheaply valued ETFs
Measured against the look-through fair value of the holdings (sufficiently covered funds only). Green means below fair value, red above. Not financial advice.
- 1 CHIU Global X MSCI China Utilities ETF +76.9 % below FV
- 2 MCHI iShares MSCI China ETF +41.9 % below FV
- 3 ITB iShares U.S. Home Construction ETF +37.1 % below FV
- 4 FCFY First Trust S&P 500 Diversified Free Cash Flow ETF +32.2 % below FV
- 5 VOX Vanguard Communication Services Index Fund ETF Shares +21.5 % below FV
- 6 XLC Communication Services Select Sector SPDR® Fund +20.6 % below FV
- 7 C003 Amundi Index Solutions - Amundi DivDAX I UCITS ETF EUR Distributing +19.1 % below FV
- 8 FDNI First Trust Dow Jones International Internet ETF +15.2 % below FV
- 9 SHRY First Trust Bloomberg Shareholder Yield ETF +14.6 % below FV
- 10 TAN Invesco Solar ETF +14.5 % below FV
Frequently asked about IBB
Is IBB overvalued?
What is the fair value of IBB?
How do you calculate the fair value of an ETF?
Which stocks drive the valuation of IBB?
What is the expense ratio of IBB?
How we value this ETF
An ETF has no fair value of its own like a single stock. We build it bottom up: every holding has a fair value and a quality score on our pages. Weighted by portfolio share, that gives iShares Biotechnology ETF an average of how cheap or expensive its companies currently sit versus fair value, and how high their average quality is.
As of: Oct 15, 2026
The look-through is a computed summary of public fundamentals and is no substitute for your own research.