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TG Therapeutics Inc (TGTX) Fair Value & Analysis

Healthcare · US · Market cap $8.4B · ISIN US88322Q1085

What is TG Therapeutics Inc really worth?

TT TG Therapeutics Inc logo TG Therapeutics Inc TGTX · US
Price$56.71
Fair Value$35.81
Upside−36.9%
Quality53/100

A solid business, but trading 58% above our fair value of $35.81.

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Strengths

Highly profitable · 66.0% net margin
Ranks above peers (8/13)
Wide moat 74/100

Risks

!Mixed Growth (revenue 5y +426.7 %/yr)
!Low debt · negative free cash flow
!Evidence only medium, so the estimate is less certain
!The models disagree: range $19.57 to $81.62
Evidence: Medium Range $19.57 – $81.62

Fair value as of: Aug 18, 2026

From 15 valuation models · updated 17 days ago

Share price +16.4% over the past month.

What runs behind every stock

69 individual criteria per stock, every one traceable See the method →

What matters now

  • The model range is unusually wide ($19.57 to $81.62). The outcome hinges heavily on assumptions, so read the point estimate with caution.
  • Solid but not exceptional quality (53/100) and above fair value, neither a clear bargain nor a standout compounder.

Price vs Fair Value (5 years)

$59.06 $3.74 Fair Value $35.81 Jun 2021 Sep 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Aug 18, 2026.

How to read this chart

60‑month range $3.74 – $59.06 · fair‑value band $19.57 – $81.62 · the $56.71 price screens above the $35.81 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Aug 18, 2026.

Full chart & analysis →

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Analysis

TG Therapeutics Inc (TGTX) currently trades at $56.71, while our model-based Fair Value estimate is $35.81, implying the stock looks roughly 58.4% overvalued today. The Quality Score stands at 53/100 (solid quality), in the Healthcare sector. Bull case: the Growth Earnings group reads highest at a median of $135.72 per share, and 6 of the 15 models we run sit above the $56.71 price. Bear case: the Economic Profit group reads lowest at $10.14, and 9 of the 15 models stay below the price. Evidence for this calculation is medium.

Over the trailing twelve months, TG Therapeutics Inc generated revenue of $700M at a net margin of 66.0%. Revenue grew 69.6% year over year. It earns a return on equity of 112.6%. Net debt stands at $182M. Fundamentals as of Aug 18, 2026

Our scenario range runs from $19.57 (bear case) to $81.62 (bull case); at $56.71, the current price sits within that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. Analysts expect earnings well below the last reported figure (earnings in transition, for example expiring patents or contracts); a fair value that looks fair on trailing earnings may then be too optimistic. The share trades near its 52-week high and 124% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at −59% fair-value upside, at −37%, TGTX screens cheaper than that median.

Fair Value models

This estimate rests on fiscal year 2025 figures, and about 8 months have passed since. In that time the company retained roughly $1.94 per share, which is 5.4 % of the fair value. The fair value deliberately does not add this in: the models value reported figures, not a projection.

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted, family-balanced blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small. Every input is real reported data, nothing guessed.

Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
EPV best evidence $5.50 $6.54 $7.44 74
ROIC Compounder $6.97 $10.14 $12.90 69
Owner Earnings $42.27 $95.01 $201.65 68
All 15 models by family
DCF Models
Owner Earnings $42.27 $95.01 $201.65 68
Earnings-Based
Graham-Dodd $19.86 $138.53 $194.40 61
Lynch FV $71.57 $102.24 $132.91 59
PEG = 1.0 $71.57 $102.24 $132.91 55
EPV best evidence $5.50 $6.54 $7.44 74
Multiples
P/E Multiple $48.20 $64.27 $80.33 63
P/S Multiple $10.57 $14.09 $17.61 58
P/B Multiple $14.29 $19.05 $23.81 55
EV/EBIT $9.18 $12.61 $16.03 66
EV/EBITDA $7.38 $10.20 $13.02 67
EV/Revenue $6.24 $9.39 $12.53 53
Asset-Based
NCAV (Graham) $2.12 $2.84 $4.23 54
Economic Profit
Residual Income $25.14 $43.77 $1,145 61
ROIC Compounder $6.97 $10.14 $12.90 69
Growth Earnings
Growth-Adj P/E $95.00 $135.72 $176.43 65

Widest divergence: Growth Earnings ($135.72) versus Asset-Based ($2.84). Highest evidence: EPV (74).

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Key figures & financial health

P/E ratio 19.8
P/S ratio 14.4 P/E × margin
EPS (TTM) $2.86 price ÷ EPS = P/E 19.8
Net margin 72.6% FY2025
Return on equity 113% TTM
Return on assets (EBIT) −35.7% avg 5y
More key figures
Profitability
Operating margin 17.0% TTM
Growth
Revenue (TTM) $700M TTM
Revenue growth (YoY) +69.6% 3y avg +505%
EPS growth (YoY) +300%
Balance sheet & cash flow
Free cash flow −$25.0M FY2025
Net debt $182M FY2025

Figures from reported company fundamentals · as of Aug 18, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 53/100

Of which business quality 52 · Market factors (momentum, volatility) 77

Profitability 85
Margins and returns on capital today
Quality Growth 72
Are margins and returns improving?
Cashflow 3
Earnings quality: real cash, not paper profit
Fin. Strength 67
Balance sheet, leverage, solvency risk
Investment 33
Disciplined investing over empire-building
Low Volatility 25
Calm price path (market factor)
Momentum 100
Price trend over the last 3–12 months (market factor)
52W Momentum 96
Distance to the 52-week high (market factor)
Net Issuance 46
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

All values are scores from 0 to 100 (100 = best against fixed, research-based bands), not percentages. The three market factors (momentum, 52-week proximity, low volatility) are displayed but carry zero weight in the headline number: market sentiment is not a business property.

About the company

TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally.

Full company description

TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally. The company provides BRIUMVI, an anti-CD20 monoclonal antibody for the treatment of adult patients with relapsing forms of multiple sclerosis (RMS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. The company's development pipeline comprises Ublituximab IV, glycoengineered anti-CD20 mAb for the treatment of relapsing MS; TG-1701 is an orally available and covalently bound Bruton's tyrosine kinase (BTK) inhibitor that exhibits selectivity to BTK in vitro kinase screening; and TG-1801, a bispecific CD47 and CD19 antibody. Its research pipeline includes various investigational medicines. The company has license agreements with LFB Biotechnologies S.A.S; GTC Biotherapeutics; LFB/GTC LLC; Ildong Pharmaceutical Co. Ltd.; and Jiangsu Hengrui Medicine Co. The company was incorporated in 1993 and is based in Morrisville, North Carolina.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

TG Therapeutics Inc reported revenue of $616M in FY2025 versus $6.7M in FY2021, a compound +209.8%/yr. Reported net income was $447M in FY2025.

Growth Quality 59/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$616M
Latest YoY
+87.3%
Avg. revenue growth/yr (3Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+504.9%
Avg. revenue growth/yr (5Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+426.7%
Avg. revenue growth/yr (29Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+35.1%
Value creation/yr We only publish this rate when it is defensible. Reason: rate outside our plausibility band
not computed
Revenue +209.8%/yr
FY21 $6.7M
FY22 $2.8M
FY23 $234M
FY24 $329M
FY25 $616M
Net income
FY21 −$348M
FY22 −$224M
FY23 $12.7M
FY24 $23.4M
FY25 $447M

TGTX screens 58% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Cite: Fair Value Calculator (2026). "TG Therapeutics Inc Fair Value". https://www.fairvalue-calculator.com/stock/TGTX

Recent news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Biotechnology · 622 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 53 · Above median
Fair Value upside −37% · Above median
Return on equity (TTM) 113% · Top 25%
Return on assets 9% · Top 25%
Net margin (TTM) 66% · Top 25%
Operating margin (TTM) 17% · Top 25%
Revenue growth 70% · Top 25%
Debt / equity 0.38× · Higher than 75% of peers

Valuation Multiples vs Biotechnology median · lower = cheaper

P/E (TTM) 19.8× · Cheaper than median
P/B 12.96× · Pricier than 75% of peers
P/S (TTM) 11.99× · Pricier than 75% of peers
EV/EBITDA 57.3× · Pricier than 75% of peers
PEG 1.61× · Pricier than median

Strength profile in five axes (Snowflake)

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE0 · sector 0
FUTURE100 · sector 0
PAST100 · sector 0
HEALTH81 · sector 98
DIVIDEND0 · sector 26

VALUE 0: the price sits above our fair-value range.

Insider activity: 45/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Aug 18, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $547.55 $278.78 −49%
Regeneron Pharmaceuticals, Inc REGN $807.71 $594.40 −26%
argenx SE ARGX €877.60 €292.84 −67%
Samsung Biologics Co 207940 1,518,000 KRW 1,055,793 KRW −30%
CSL Limited CSL A$174.50 A$141.68 −19%
Alnylam Pharmaceuticals, Inc ALNY $228.61 $51.70 −77%
Royalty Pharma plc RPRX $60.58 $24.22 −60%
Celltrion, Inc 068270 190,700 KRW 74,519 KRW −61%
BeOne Medicines AG ONC $362.51 $111.35 −69%
BioNTech SE BNTX $111.40 $45.66 −59%

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Frequently asked questions

Is TG Therapeutics Inc (TGTX) overvalued or undervalued?
As of Aug 18, 2026, our model estimates a fair value of $35.81 versus a price of $56.71, about −37% upside (overvalued).
What is the fair value of TGTX?
Our model-based fair value for TG Therapeutics Inc is $35.81 (as of Aug 18, 2026), built from audited fundamentals. The current price: $56.71.
What is the quality score of TGTX?
TG Therapeutics Inc has a Quality Score of 53/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of TG Therapeutics Inc (TGTX)?
TG Therapeutics Inc reported trailing-twelve-month revenue of about $700M (latest available figure, as of Aug 18, 2026).
What is the net profit margin of TGTX?
The net profit margin of TG Therapeutics Inc is about 66.0%, meaning it keeps roughly 66.0% of revenue as net income. Based on the latest reported figures.
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