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ACADIA Pharmaceuticals Inc (ACAD) Fair Value & Analysis

Healthcare · US · Market cap $4.5B · ISIN US0042251084

What is ACADIA Pharmaceuticals Inc really worth?

AP ACADIA Pharmaceuticals Inc logo ACADIA Pharmaceuticals Inc ACAD · US
Price$27.86
Fair Value$21.90
Upside−21.4%
Quality63/100

A solid business, but trading 27% above our fair value of $21.90.

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Strengths

Highly profitable · 34.3% net margin
Low debt · generates free cash flow
Ranks above peers (9/14)

Risks

!Mixed Growth (revenue 5y +19.4 %/yr)
!Moderate moat 59/100
!Evidence only medium, so the estimate is less certain
!Weak on valuation: 5 out of 100
Evidence: Medium Range $16.39 – $34.30

Fair value as of: Aug 29, 2026

From 24 valuation models · updated 7 days ago

Share price +2.6% over the past month.

What runs behind every stock

69 individual criteria per stock, every one traceable See the method →

What matters now

  • Solid but not exceptional quality (63/100) and above fair value, neither a clear bargain nor a standout compounder.
  • A fairly wide model range ($16.39 to $34.30) leaves room in how you read the outcome.

Price vs Fair Value (5 years)

$33.47 $13.01 Fair Value $21.90 Jun 2021 Sep 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Aug 29, 2026.

How to read this chart

60‑month range $13.01 – $33.47 · fair‑value band $16.39 – $34.30 · the $27.86 price screens above the $21.90 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Aug 29, 2026.

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Analysis

ACADIA Pharmaceuticals Inc (ACAD) currently trades at $27.86, while our model-based Fair Value estimate is $21.90, implying the stock looks roughly 27.2% overvalued today. The Quality Score stands at 63/100 (solid quality), in the Healthcare sector. Bull case: the Growth Earnings group reads highest at a median of $106.09 per share, and 9 of the 24 models we run sit above the $27.86 price. Bear case: the Asset-Based group reads lowest at $4.80, and 15 of the 24 models stay below the price. Evidence for this calculation is medium.

Over the trailing twelve months, ACADIA Pharmaceuticals Inc generated revenue of $1.1B at a net margin of 34.3%. Revenue grew 9.7% year over year. It earns a return on equity of 37.3%. The balance sheet holds a net cash position of $126M. Fundamentals as of Aug 29, 2026

Our scenario range runs from $16.39 (bear case) to $34.30 (bull case); at $27.86, the current price sits within that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. Analysts expect earnings well below the last reported figure (earnings in transition, for example expiring patents or contracts); a fair value that looks fair on trailing earnings may then be too optimistic. The share trades about 2% below its 52-week high and 41% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at −59% fair-value upside, at −21%, ACAD screens cheaper than that median.

Fair Value models

This estimate rests on fiscal year 2025 figures, and about 8 months have passed since. In that time the company retained roughly $1.50 per share, which is 6.9 % of the fair value. The fair value deliberately does not add this in: the models value reported figures, not a projection.

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted, family-balanced blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small. Every input is real reported data, nothing guessed.

Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
FCF DCF $10.80 $16.07 $32.51 74
EPV $6.05 $6.84 $7.52 74
Growth DCF $10.21 $18.50 $31.84 73
All 24 models by family
DCF Models
FCF DCF $10.80 $16.07 $32.51 74
Owner Earnings $35.56 $77.54 $162.43 68
5Y Revenue Exit $8.24 $13.23 $23.67 68
5Y EBITDA Exit $9.11 $14.99 $26.53 70
5Y P/E Exit $31.65 $76.32 $138.37 65
10Y Revenue Exit $8.88 $17.59 $22.93 64
10Y EBITDA Exit $9.74 $19.42 $35.98 63
10Y P/E Exit $25.82 $66.85 $136.94 57
Earnings-Based
Graham-Dodd $15.53 $108.28 $151.96 61
Lynch FV $55.94 $79.92 $103.89 59
PEG = 1.0 $55.94 $79.92 $103.89 55
EPV $6.05 $6.84 $7.52 74
Multiples
P/E Multiple $37.68 $50.23 $62.79 63
P/S Multiple $16.43 $21.90 $27.38 58
P/B Multiple $24.19 $32.26 $40.32 55
EV/EBIT $8.84 $11.44 $14.04 66
EV/EBITDA $8.19 $10.57 $12.95 67
EV/Revenue $6.61 $8.99 $11.38 54
Asset-Based
NCAV (Graham) $3.58 $4.80 $7.17 54
Growth DCF
Growth DCF $10.21 $18.50 $31.84 73
Rev-Margin DCF $8.97 $14.99 $27.61 67
Economic Profit
Residual Income $15.97 $22.35 $184.19 61
ROIC Compounder $6.05 $6.84 $8.11 70
Growth Earnings
Growth-Adj P/E $74.26 $106.09 $137.91 65

Widest divergence: Growth Earnings ($106.09) versus Asset-Based ($4.80). Highest evidence: FCF DCF (74).

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Key figures & financial health

P/E ratio 12.6
P/S ratio 4.60 P/E × margin
EPS (TTM) $2.21 price ÷ EPS = P/E 12.6
Net margin 36.5% FY2025
Return on equity 37.3% TTM
Return on assets (EBIT) −9.2% avg 5y
More key figures
Profitability
Operating margin −1.7% TTM
Growth
Revenue (TTM) $1.1B TTM
Revenue growth (YoY) +9.7% 3y avg +27.5%
EPS growth (YoY) −81.8%
Balance sheet & cash flow
Free cash flow $105M FY2025
Net cash $126M FY2025

Figures from reported company fundamentals · as of Aug 29, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 63/100

Of which business quality 65 · Market factors (momentum, volatility) 66

Profitability 89
Margins and returns on capital today
Quality Growth 57
Are margins and returns improving?
Cashflow 48
Earnings quality: real cash, not paper profit
Fin. Strength 88
Balance sheet, leverage, solvency risk
Investment 33
Disciplined investing over empire-building
Low Volatility 63
Calm price path (market factor)
Momentum 67
Price trend over the last 3–12 months (market factor)
52W Momentum 69
Distance to the 52-week high (market factor)
Net Issuance 57
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

All values are scores from 0 to 100 (100 = best against fixed, research-based bands), not percentages. The three market factors (momentum, 52-week proximity, low volatility) are displayed but carry zero weight in the headline number: market sentiment is not a business property.

About the company

ACADIA Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of medicines for neurological and rare disease in North America.

Full company description

ACADIA Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of medicines for neurological and rare disease in North America. The company offers NUPLAZID (pimavanserin), a selective serotonin inverse agonist/antagonist for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis; and DAYBUE, a novel synthetic analog of the amino-terminal tripeptide of insulin-like growth factor 1 to treat the symptoms of Rett syndrome by reducing neuroinflammation and supporting synaptic function. It also develops remlifanserin, which is in phase 2 clinical trial for the treatment of alzheimer's disease psychosis and lewy body dementia psychosis; ACP-211, which is in phase 2 clinical trial to treat major depressive disorder; ACP-711, which is in phase I clinical trial for the treatment of essential tremor; and ACP-271, a GPR88 agonist for the treatment of tardive dyskinesia and huntington's disease and is in phase I trial. In addition, the company develops ACP-2591, a cGP analogue which is in Phase 1 clinical trial to treat rett syndrome and fragile X syndrome; and STOKE Antisense Oligonucleotide Program, which is in discovery program for SYNGAP1 syndrome. It has a license agreement with Neuren Pharmaceuticals Limited to trofinetide for Rett syndrome and other indications; and a license and collaboration agreement with Stoke Therapeutics, Inc. to discover, develop, and commercialize novel RNA-based medicines for the potential treatment of severe and rare genetic neurodevelopmental diseases of the CNS. The company was formerly known as Receptor Technologies, Inc. and changed its name ACADIA Pharmaceuticals Inc. in 1997. ACADIA Pharmaceuticals Inc. was incorporated in 1993 and is headquartered in San Diego, California.

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

ACADIA Pharmaceuticals Inc reported revenue of $1.1B in FY2025 versus $484M in FY2021, a compound +22.0%/yr. Reported net income was $391M in FY2025.

Growth Quality 77/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$1.1B
Latest YoY
+11.9%
Avg. revenue growth/yr (3Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+27.5%
Avg. revenue growth/yr (5Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+19.4%
Avg. revenue growth/yr (25Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+24.7%
Value creation/yr We only publish this rate when it is defensible. Reason: no profitable base year
not computed
Revenue +22.0%/yr
FY21 $484M
FY22 $517M
FY23 $726M
FY24 $958M
FY25 $1.1B
Net income
FY21 −$168M
FY22 −$216M
FY23 −$61.3M
FY24 $226M
FY25 $391M

ACAD screens 27% overvalued. Compare with Vertex Pharmaceuticals Incorporated →

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Cite: Fair Value Calculator (2026). "ACADIA Pharmaceuticals Inc Fair Value". https://www.fairvalue-calculator.com/stock/ACAD

Recent news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Biotechnology · 622 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 63 · Top 25%
Fair Value upside −21% · Above median
Return on equity (TTM) 37% · Top 25%
Return on assets 4% · Top 25%
Net margin (TTM) 34% · Top 25%
Operating margin (TTM) −2% · Below median
Revenue growth 10% · Above median

Valuation Multiples vs Biotechnology median · lower = cheaper

P/E (TTM) 12.6× · Cheaper than 75% of peers
P/B 3.66× · Pricier than 75% of peers
P/S (TTM) 4.10× · Cheaper than median
P/FCF 42.7× · Pricier than 75% of peers
EV/EBITDA 46.5× · Pricier than 75% of peers
PEG 50.86× · Pricier than 75% of peers

Strength profile in five axes (Snowflake)

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE5 · sector 0
FUTURE49 · sector 0
PAST100 · sector 0
HEALTH100 · sector 98
DIVIDEND0 · sector 26

Insider activity: 44/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Biotechnology stocks, each showing price versus our Fair Value estimate (as of Aug 29, 2026).

Stock Price Fair Value vs Fair Value
Vertex Pharmaceuticals Incorporated VRTX $547.55 $278.78 −49%
Regeneron Pharmaceuticals, Inc REGN $807.71 $594.40 −26%
argenx SE ARGX €877.60 €292.84 −67%
Samsung Biologics Co 207940 1,518,000 KRW 1,055,793 KRW −30%
CSL Limited CSL A$174.50 A$141.68 −19%
Alnylam Pharmaceuticals, Inc ALNY $228.61 $51.70 −77%
Royalty Pharma plc RPRX $60.58 $24.22 −60%
Celltrion, Inc 068270 190,700 KRW 74,519 KRW −61%
BeOne Medicines AG ONC $362.51 $111.35 −69%
BioNTech SE BNTX $111.40 $45.66 −59%

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Frequently asked questions

Is ACADIA Pharmaceuticals Inc (ACAD) overvalued or undervalued?
As of Aug 29, 2026, our model estimates a fair value of $21.90 versus a price of $27.86, about −21% upside (overvalued).
What is the fair value of ACAD?
Our model-based fair value for ACADIA Pharmaceuticals Inc is $21.90 (as of Aug 29, 2026), built from audited fundamentals. The current price: $27.86.
What is the quality score of ACAD?
ACADIA Pharmaceuticals Inc has a Quality Score of 63/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of ACADIA Pharmaceuticals Inc (ACAD)?
ACADIA Pharmaceuticals Inc reported trailing-twelve-month revenue of about $1.1B (latest available figure, as of Aug 29, 2026).
What is the net profit margin of ACAD?
The net profit margin of ACADIA Pharmaceuticals Inc is about 34.3%, meaning it keeps roughly 34.3% of revenue as net income. Based on the latest reported figures.
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