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Natera Inc (NTRA) Fair Value & Analysis

Healthcare · US · Market cap $38.6B · ISIN US6323071042

What is Natera Inc really worth?

NI Natera Inc logo Natera Inc NTRA · US
Price$327.67
Fair Value$15.92
Upside−95.1%
Quality37/100

Structural break: The valuation model sees a lasting decline in earnings power for this stock, the confidence band is broken. Treat the target with caution.

Below-average quality, and trading another 1,958% above our fair value of $15.92.

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Strengths

Low debt · generates free cash flow

Risks

!Mixed Growth (revenue 5y +42.6 %/yr)
!Loss-making · -9.1% net margin
!Trails peers (1/12)
!Narrow moat 15/100
!Evidence only low, so the estimate is less certain
!Weak on dividend: 2 out of 100
Evidence: Low Range $12.95 – $18.89

Fair value as of: Aug 27, 2026

From 9 valuation models · updated 9 days ago

Share price +19.1% over the past month.

What runs behind every stock

69 individual criteria per stock, every one traceable See the method →

What matters now

  • The price sits above even our optimistic bull case ($18.89). The favourable scenario is already priced in.
  • Weak quality (37/100) and above fair value at the same time, the margin of safety is missing on both counts.
  • The large gap to fair value rests on thin data (low evidence): fewer applicable models and a shorter history. Read it with extra caution.

Price vs Fair Value (5 years)

$338.70 $28.13 Fair Value $15.92 Jun 2021 Sep 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Aug 27, 2026.

How to read this chart

60‑month range $28.13 – $338.70 · fair‑value band $12.95 – $18.89 · the $327.67 price screens above the $15.92 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Aug 27, 2026.

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Analysis

Natera Inc (NTRA) currently trades at $327.67, while our model-based Fair Value estimate is $15.92, implying the stock looks roughly 1,957.6% overvalued today. The Quality Score stands at 37/100 (below-average quality), in the Healthcare sector. Bull case: the DCF Models group reads highest at a median of $25.72 per share, and 0 of the 9 models we run sit above the $327.67 price. Bear case: the Dividend Discount group reads lowest at $3.37, and 9 of the 9 models stay below the price. Evidence for this calculation is low.

Over the trailing twelve months, Natera Inc generated revenue of $2.5B at a net margin of −9.1%. Revenue grew 38.8% year over year. It earns a return on equity of −15.0%. The balance sheet holds a net cash position of $862M. Fundamentals as of Aug 27, 2026

Our scenario range runs from $12.95 (bear case) to $18.89 (bull case); at $327.67, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades near its 52-week high and 149% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at −54% fair-value upside, at −95%, NTRA screens richer than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted, family-balanced blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small. Every input is real reported data, nothing guessed.

Note: the current price implies far more future growth than the conservative anchors of our models allow (base growth is deliberately capped, we do not regard such extreme rates as sustainable). Our models are not designed for expectations this high; that is why the individual models scatter extremely ($3.37 to $29.48). Read the values as a conservative anchor, not as a price target.
Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
FCF DCF $18.36 $25.72 $49.13 75
Growth DCF $17.60 $29.48 $48.94 74
5Y Revenue Exit $14.66 $21.02 $34.30 69
All 9 models by family
DCF Models
FCF DCF $18.36 $25.72 $49.13 75
5Y Revenue Exit $14.66 $21.02 $34.30 69
10Y Revenue Exit $15.59 $26.88 $33.84 65
Dividend Discount
Gordon GGM $1.92 $4.00 $6.34 64
DDM Multi-Stage $1.92 $3.37 $4.20 64
Multiples
EV/Revenue $12.47 $15.44 $18.41 54
Asset-Based
NCAV (Graham) $5.98 $8.01 $11.96 54
Growth DCF
Growth DCF $17.60 $29.48 $48.94 74
Rev-Margin DCF $15.59 $23.25 $39.31 69

Widest divergence: DCF Models ($25.72) versus Dividend Discount ($3.37). Highest evidence: FCF DCF (75).

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Key figures & financial health

P/S ratio 12.3 TTM
EPS (TTM) $−1.62
Dividend yield 0.1%
Net margin −9.0% FY2025
Return on equity −15.0% TTM
Return on assets (EBIT) −26.7% avg 5y
More key figures
Profitability
Operating margin −12.4% TTM
Growth
Revenue (TTM) $2.5B TTM
Revenue growth (YoY) +38.8% 3y avg +41.1%
Balance sheet & cash flow
Free cash flow $109M FY2025
Net cash $862M FY2025

Figures from reported company fundamentals · as of Aug 27, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 37/100

Of which business quality 45 · Market factors (momentum, volatility) 78

Profitability 33
Margins and returns on capital today
Quality Growth 60
Are margins and returns improving?
Cashflow 33
Earnings quality: real cash, not paper profit
Fin. Strength 97
Balance sheet, leverage, solvency risk
Investment 29
Disciplined investing over empire-building
Low Volatility 25
Calm price path (market factor)
Momentum 100
Price trend over the last 3–12 months (market factor)
52W Momentum 100
Distance to the 52-week high (market factor)
Net Issuance 0
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

All values are scores from 0 to 100 (100 = best against fixed, research-based bands), not percentages. The three market factors (momentum, 52-week proximity, low volatility) are displayed but carry zero weight in the headline number: market sentiment is not a business property.

About the company

Natera, Inc., a diagnostics company, engages in the development and commercialization of molecular testing services worldwide.

Full company description

Natera, Inc., a diagnostics company, engages in the development and commercialization of molecular testing services worldwide. It offers Signatera, a personalized ctDNA blood test for MRD assessment, early recurrence monitoring, and evaluation of treatment response in patients previously diagnosed with cancer; Latitude, a blood-based MRD test for colorectal cancer; Altera, a tissue based comprehensive genomic profiling test; and Empower, a hereditary cancer screening test. The company also provides Panorama, a non-invasive prenatal test; Horizon, a carrier screening test; Fetal Focus, a single-gene NIPT, or sgNIPT, that screens for 21 single-gene inherited conditions; and Vistara, a single-gene NIPT, which screens for 25 single-gene conditions. In addition, it offers Anora, which tests and analyzes miscarriage tissue from women who have experienced one or more pregnancy losses; Empower, a hereditary cancer screening test; Prospera, a test to assess active rejection in patients who have undergone solid organ transplantation; Renasight, a kidney gene panel test; and Constellation software, a cloud-based distribution model. Further, the company provides NateraCore, a platform to support the patient and provider experience; phlebotomy services; and EMR integration services. The company serves independent laboratories, national and regional reference laboratories, medical centers and physician practices for its screening tests, research laboratories, and pharmaceutical companies through its direct sales force and laboratory distribution partners, as well as Constellation licensees under its cloud-based distribution model. It has a partnership agreement with BGI Genomics Co., Ltd. to develop, manufacture, and commercialize NGS-based genetic testing assays for clinical and commercial use. The company has a collaboration with Diakonos Oncology Corp. to assess molecular response in patients with refractory melanoma. The company was formerly known as Gene Security Network, LLC and changed its name to Natera, Inc. in Januar

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Natera Inc reported revenue of $2.3B in FY2025 versus $625M in FY2021, a compound +38.6%/yr. Reported net income was −$208M in FY2025.

Growth Quality 62/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$2.3B
Latest YoY
+35.9%
Avg. revenue growth/yr (3Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+41.1%
Avg. revenue growth/yr (5Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+42.6%
Avg. revenue growth/yr (13Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+47.9%
Value creation/yr We only publish this rate when it is defensible. Reason: fiscal 2025 is a loss year, no rate is defined from a loss
not computed
Revenue +38.6%/yr
FY21 $625M
FY22 $820M
FY23 $1.1B
FY24 $1.7B
FY25 $2.3B
Net income
FY21 −$472M
FY22 −$548M
FY23 −$435M
FY24 −$190M
FY25 −$208M

NTRA screens 1,958% overvalued. Compare with Thermo Fisher Scientific Inc →

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Cite: Fair Value Calculator (2026). "Natera Inc Fair Value". https://www.fairvalue-calculator.com/stock/NTRA

Recent news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Diagnostics & Research · 130 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 37 · Bottom 25%
Fair Value upside −95% · Bottom 25%
Return on assets −9% · Bottom 25%
Net margin (TTM) −9% · Below median
Operating margin (TTM) −12% · Below median
Revenue growth 39% · Top 25%
Dividend yield (TTM) 0.1% · Bottom 25%
Debt / equity 0.17× · Higher than median

Valuation Multiples vs Diagnostics & Research median · lower = cheaper

P/B 22.57× · Pricier than 75% of peers
P/S (TTM) 15.45× · Pricier than 75% of peers
P/FCF 354.2× · Pricier than 75% of peers

Strength profile in five axes (Snowflake)

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUEFUTUREPASTHEALTHDIVIDEND
This stock
VALUEFUTUREPASTHEALTHDIVIDEND
Sector peers
VALUE0 · sector 0
FUTURE100 · sector 30
PAST0 · sector 12
HEALTH92 · sector 96
DIVIDEND2 · sector 20

VALUE 0: the price sits above our fair-value range.

Insider activity: 40/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

Similar stocks

10 more Diagnostics & Research stocks, each showing price versus our Fair Value estimate (as of Aug 27, 2026).

Stock Price Fair Value vs Fair Value
Thermo Fisher Scientific Inc TMO $630.70 $308.19 −51%
Danaher Corporation DHR $215.68 $103.88 −52%
WuXi AppTec Co 2359 HK$189.30 HK$150.16 −21%
Lonza Group LONN CHF 576.60 CHF 259.80 −55%
IDEXX Laboratories, Inc IDXX $556.69 $255.77 −54%
Agilent Technologies, Inc A $149.93 $61.53 −59%
Waters Corporation WAT $416.15 $121.96 −71%
IQVIA Holdings IQV $236.66 $132.17 −44%
Illumina, Inc ILMN $215.59 $95.51 −56%
Mettler-Toledo International Inc MTD $1,419 $615.78 −57%

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Frequently asked questions

Is Natera Inc (NTRA) overvalued or undervalued?
As of Aug 27, 2026, our model estimates a fair value of $15.92 versus a price of $327.67, about −95% upside (overvalued).
What is the fair value of NTRA?
Our model-based fair value for Natera Inc is $15.92 (as of Aug 27, 2026), built from audited fundamentals. The current price: $327.67.
What is the quality score of NTRA?
Natera Inc has a Quality Score of 37/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Natera Inc (NTRA)?
Natera Inc reported trailing-twelve-month revenue of about $2.5B (latest available figure, as of Aug 27, 2026).
What is the net profit margin of NTRA?
The net profit margin of Natera Inc is about −9.1%, meaning it is currently running at a net loss. Based on the latest reported figures.
Does Natera Inc pay a dividend?
Natera Inc currently shows a dividend yield of about 0.10% relative to its recent price (as of Aug 27, 2026).
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