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Natera, Inc (NTRA) Fair Value & Analysis

Healthcare · US · Market cap $38.6B

NI Natera, Inc logo Natera, Inc NTRA · US
Price$310.78
Fair Value$15.92
Upside-94.9%
Quality37/100
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Mixed Growth
Loss-making · -9.1% net margin
Low debt · generates free cash flow
Trails peers (1/11)
Narrow moat 15/100
Evidence: Medium Range $12.95 – $18.89 Share as image

Fair value as of: Aug 13, 2026

From 9 valuation models · updated yesterday

Share price +14.0% over the past month.

Below-average quality, and screening another 95% overvalued on our models.

What matters now

  • The price sits above even our optimistic bull case ($18.89). The favourable scenario is already priced in.
  • Weak quality (37/100) and above fair value at the same time, the margin of safety is missing on both counts.
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Price vs Fair Value (5 years)

$322.10 $28.13 Fair Value $15.92 May 2021 Aug 2026

White line = price, green steps = our fair value per fiscal year, dashed = 300-day average. As of Aug 13, 2026.

How to read this chart

60‑month range $28.13 – $322.10 · fair‑value band $12.95 – $18.89 · the $310.78 price screens above the $15.92 fair value. Green steps = our fair value per fiscal year (point-in-time, no hindsight). Dashed = 300-day average. As of Aug 13, 2026.

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Analysis

Natera, Inc (NTRA) currently trades at $310.78, while our model-based Fair Value estimate is $15.92, implying the stock looks roughly 94.9% overvalued today. The Quality Score stands at 37/100 (below-average quality), in the Healthcare sector. Bear case: priced above our estimate, the market already discounts strong expectations. Bull case: above-average quality can justify a premium, the entry price still matters most (evidence: medium).

Over the trailing twelve months, Natera, Inc generated revenue of $2.5B at a net margin of -9.1%. Revenue grew 38.8% year over year. It earns a return on equity of -15.0%. The balance sheet holds a net cash position of $862M. Fundamentals as of Aug 13, 2026

Our scenario range runs from $12.95 (bear case) to $18.89 (bull case); at $310.78, the current price sits above that range. Bear and bull are the same models run on conservative and optimistic assumptions (margins, growth, valuation multiples), so a plausible valuation range, not a price target. The share trades near its 52-week high and 136% above its 52-week low, currently above its 200-day average. For context, the median of 10 Healthcare peers we cover trades at -50% fair-value upside, at -95%, NTRA screens richer than that median.

Fair Value models

Each model estimates fair value its own way; the Fair Value above is the evidence-weighted blend. Evidence (0–100) measures how completely this model’s inputs are available: well-fed models carry more weight in the blend. The spread across models is intentional, each one stresses a different value driver; dividend models, for instance, come out structurally low when payout is small.

Note: the current price implies far more future growth than the conservative anchors of our models allow (base growth is deliberately capped, we do not regard such extreme rates as sustainable). Our models are not designed for expectations this high; that is why the individual models scatter extremely ($3.37 to $29.48). Read the values as a conservative anchor, not as a price target.
Model Bear Bear = the cautious scenario: the same model computed with conservative anchors (lower growth, margins and valuation multiples). Together with Bull it frames a plausible valuation range, not a price target.BaseBull Bull = the optimistic scenario: the same model computed with favourable anchors (higher growth, margins and valuation multiples). Together with Bear it frames a plausible valuation range, not a price target. Evidence
Highest evidence
Growth DCF $17.60 $29.48 $48.94 80
Rev-Margin DCF $15.59 $23.25 $39.31 74
Gordon GGM $1.92 $4.00 $6.34 70
All 9 models by family
DCF Models
FCF DCF $18.36 $25.72 $49.13 38
5Y Revenue Exit $14.66 $21.02 $34.30 39
10Y Revenue Exit $15.59 $26.88 $33.84 36
Dividend Discount
Gordon GGM $1.92 $4.00 $6.34 70
DDM Multi-Stage $1.92 $3.37 $4.20 61
Multiples
EV/Revenue $12.47 $15.44 $18.41 43
Asset-Based
NCAV (Graham) $5.98 $8.01 $11.96 50
Growth DCF
Growth DCF $17.60 $29.48 $48.94 80
Rev-Margin DCF $15.59 $23.25 $39.31 74

Widest divergence: DCF Models ($25.72) versus Dividend Discount ($3.37). Highest evidence: Growth DCF (80).

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Key figures & financial health

Revenue (TTM) $2.5B
Revenue growth (YoY) +38.8%
Net margin -9.1%
Return on equity -15.0%
Free cash flow $109M FY2025
Operating margin -12.4%
More key figures
EPS (TTM) $-1.62
Net cash $862M FY2025

Figures from reported company fundamentals · as of Aug 13, 2026. TTM = trailing twelve months.

Quality Score breakdown

Overall quality 37/100

Of which business quality 45 · Market factors (momentum, volatility) 77

Profitability 33
Margins and returns on capital today
Quality Growth 60
Are margins and returns improving?
Cashflow 33
Earnings quality: real cash, not paper profit
Fin. Strength 97
Balance sheet, leverage, solvency risk
Investment 29
Disciplined investing over empire-building
Low Volatility 25
Calm price path (market factor)
Momentum 98
Price trend over the last 3–12 months (market factor)
52W Momentum 100
Distance to the 52-week high (market factor)
Net Issuance 0
Buybacks instead of dilution

Non-valuation factor families (profitability, growth, cashflow, financial strength, momentum …), each academically grounded. Valuation itself sits in the Fair Value and is deliberately excluded here to avoid double-counting.

About the company

Natera, Inc., a diagnostics company, engages in the development and commercialization of molecular testing services worldwide.

Full company description

Natera, Inc., a diagnostics company, engages in the development and commercialization of molecular testing services worldwide. It offers Signatera, a personalized ctDNA blood test for MRD assessment, early recurrence monitoring, and evaluation of treatment response in patients previously diagnosed with cancer; Latitude, a blood-based MRD test for colorectal cancer; Altera, a tissue based comprehensive genomic profiling test; and Empower, a hereditary cancer screening test. The company also provides Panorama, a non-invasive prenatal test; Horizon, a carrier screening test; Fetal Focus, a single-gene NIPT, or sgNIPT, that screens for 21 single-gene inherited conditions; and Vistara, a single-gene NIPT, which screens for 25 single-gene conditions. In addition, it offers Anora, which tests and analyzes miscarriage tissue from women who have experienced one or more pregnancy losses; Empower, a hereditary cancer screening test; Prospera, a test to assess active rejection in patients who have undergone solid organ transplantation; Renasight, a kidney gene panel test; and Constellation software, a cloud-based distribution model. Further, the company provides NateraCore, a platform to support the patient and provider experience; phlebotomy services; and EMR integration services. The company serves independent laboratories, national and regional reference laboratories, medical centers and physician practices for its screening tests, research laboratories, and pharmaceutical companies through its direct sales force and laboratory distribution partners, as well as Constellation licensees under its cloud-based distribution model. It has a partnership agreement with BGI Genomics Co., Ltd. to develop, manufacture, and commercialize NGS-based genetic testing assays for clinical and commercial use. The company has a collaboration with Diakonos Oncology Corp. to assess molecular response in patients with refractory melanoma. The company was formerly known as Gene Security Network, LLC and changed its name to Natera, Inc. in Januar

Company description, as reported by the company or data provider.

Revenue & earnings trend

FY2021 – FY2025 · reported fiscal years

Natera, Inc reported revenue of $2.3B in FY2025 versus $625M in FY2021, a compound +38.6%/yr. Reported net income was −$208M in FY2025.

Growth Quality 62/100
Revenue is growing, but margins or cash flow do not fully confirm the trend.
Latest Revenue (FY 2025)
$2.3B
Latest YoY
+35.9%
Avg. growth/yr (3Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+41.1%
Avg. growth/yr (5Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+42.6%
Avg. growth/yr (13Y) Measures the company's TOTAL revenue from reported annual statements: compound average growth per year (CAGR) from the fiscal year 3, 5 or N years back to the most recent comparable fiscal year. Not per share: buybacks do not change this number, and a merger can appear as a growth jump.
+47.9%
Revenue +38.6%/yr
FY21 $625M
FY22 $820M
FY23 $1.1B
FY24 $1.7B
FY25 $2.3B
Net income
FY21 −$472M
FY22 −$548M
FY23 −$435M
FY24 −$190M
FY25 −$208M

NTRA screens 95% overvalued. Compare with Thermo Fisher Scientific Inc →

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Cite: Fair Value Calculator (2026). "Natera, Inc Fair Value". https://www.fairvalue-calculator.com/stock/NTRA

Earlier news

External third-party headlines (Yahoo Finance, Reuters and others), not an editorial selection.

Peer Group

Diagnostics & Research · 135 stocks

How this stock ranks against its industry: the green marker is this stock, the band is the typical 25–75% peer range, and the tick is the median.

Quality Score 37 · Bottom 25%
Fair Value upside −95% · Bottom 25%
Return on assets -9% · Bottom 25%
Net margin (TTM) -9% · Below median
Operating margin (TTM) -12% · Below median
Revenue growth 39% · Top 25%
Debt / equity 0.17× · Higher than median

Valuation Multiples vs Diagnostics & Research median · lower = cheaper

P/B 22.57× · Pricier than 75% of peers
P/S (TTM) 15.45× · Pricier than 75% of peers
P/FCF 354.2× · Pricier than 75% of peers

Snowflake

Five quick dimensions, each 0 to 100: VALUE (fair-value potential), FUTURE (revenue growth), PAST (return on equity), HEALTH (low debt), DIVIDEND (yield). Green = this stock, grey = typical sector peer.

VALUE 0 · sector 0
FUTURE 100 · sector 25
PAST 0 · sector 12
HEALTH 92 · sector 96
DIVIDEND 0 · sector 23

VALUE 0: the price sits above our fair-value range.

Insider activity: 40/100

Values & ESG

Does this company touch areas you may want to avoid? The classification is inferred from sector and industry.

None of the checked exposures detected

ESG scores are not available for this stock yet. Values and ESG data are contextual and can differ between providers.

Similar stocks

10 more Diagnostics & Research stocks, each showing price versus our Fair Value estimate (as of Aug 13, 2026).

Stock Price Fair Value vs Fair Value
Thermo Fisher Scientific Inc TMO $603.01 $308.19 -49%
Danaher Corporation DHR $205.79 $103.88 -50%
WuXi AppTec Co 2359 HK$198.90 HK$157.39 -21%
Lonza Group LONN CHF 566.20 CHF 259.80 -54%
IDEXX Laboratories, Inc IDXX $570.58 $255.77 -55%
Agilent Technologies, Inc A $148.24 $61.53 -58%
Waters Corporation WAT $416.15 $121.96 -71%
IQVIA Holdings IQV $243.84 $132.17 -46%
Illumina, Inc ILMN $192.91 $95.51 -50%
Mettler-Toledo International Inc MTD $1,437 $615.78 -57%

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Frequently asked questions

Is Natera, Inc (NTRA) overvalued or undervalued?
As of Aug 13, 2026, our model estimates a fair value of $15.92 versus a price of $310.78, about −95% (overvalued).
What is the fair value of NTRA?
Our model-based fair value for Natera, Inc is $15.92 (as of Aug 13, 2026), built from audited fundamentals. The current price is $310.78.
What is the quality score of NTRA?
Natera, Inc has a Quality Score of 37/100. It measures business quality (profitability, growth, cash flow, balance-sheet strength, investment discipline, share issuance). Market factors such as price momentum and volatility do not enter the number; they are shown separately in the detail view.
What is the revenue of Natera, Inc (NTRA)?
Natera, Inc reported trailing-twelve-month revenue of about $2.5B (latest available figure, as of Aug 13, 2026).
What is the net profit margin of NTRA?
The net profit margin of Natera, Inc is about -9.1%, meaning it is currently running at a net loss. Based on the latest reported figures.

How we calculate Fair Value

Each company is valued through a stack of independent intrinsic-value models (DCF variants, residual-income, multiples and more), blended into one family-balanced consensus and weighted by how much trustworthy data backs it. A separate quality layer scores the fundamentals. Every input is real reported data, nothing guessed.

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